Supplement information: SAMe (S - adenosyl - L - methionin)
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| General description |
SAMe is compund made from methionine, a sulfur containing amino acids and ATP. Methionin, folate or vitamin B12 deficiences can reduce SAMe level.
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| Anti-aging role |
- osteoarthritis, fibromyalgia - depression |
| Therapeutic doses |
400 mg taken three to four times / day
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| Maximum safe level |
Not established.
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| Side effects |
- mild gastrointestinal upset
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| Contraindications |
- people with bipolar disease should avoid SAMe as it can trigger manic episodes -kidney or liver disease |
| Interactions |
- levodopa - antidepressants |