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Supplement information: SAMe (S - adenosyl - L - methionin)
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General description SAMe is compund made from methionine, a sulfur containing amino acids and ATP. Methionin, folate or vitamin B12 deficiences can reduce SAMe level.
Anti-aging role - osteoarthritis, fibromyalgia
- depression
Therapeutic doses 400 mg taken three to four times / day
Maximum safe level Not established.
Side effects - mild gastrointestinal upset
Contraindications - people with bipolar disease should avoid SAMe as it can trigger manic episodes
-kidney or liver disease
Interactions - levodopa
- antidepressants