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General description	Water soluble enzymes cofactor
Found	- yeast - liver and organ meat - egg yolk - grains - nuts, peas, beans - fish
Anti-aging role	- required for the formation of fatty acids and glucose metabolism - required for metabolism of aminoscids and carbohydrates - required for healthy hair, skin, nails, sweat glands, nerves, bone marrow and normal bone growth - may help in prevention of SIDS
Deficiency symptoms	- scaly dermatitis, sensitive skin - inflamed sore tongue - loss of appetite, nausea - depression, insomnia - muscle pain, burning sensation - sitophobia - fear of eating - paleness, anemia - heart function abnormalities - increased cholesterol - depression of immune system
Therapeutic doses	50 - 200 mcg combined with other B - complex vitamins European RDA: 150mcg
Maximum safe level	2,5 mg for long and short-term usage
Contraindications	- diabetes
Interactions	- gabapentin - phenobarbital - valproic acid
Composition formulas	- usually as ingredient of B-complex supplements or with other vitamins and minerals
Other remarks	- gut flora produce biotin in small amount

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